NBPF14

Across TCGA cell cohorts, NBPF14 mutation is significantly associated with the RNA expression of many other genes, with 755 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NBPF14-associated genes across cancer lineages are OR52N5, CTLA4, and ACD. Each is linked with NBPF14 in more than 2 cancer types. Because this analysis shows association rather than direction, both NBPF14-to-partner and partner-to-NBPF14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR52N5 grouped by NBPF14-low versus NBPF14-high in PANCREAS.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF14→partner) and Y-score (partner→NBPF14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PANCREAS	OR52N5 →	+0.008	+4.029	<.001	.007	3	2
BREAST	CTLA4 →	+0.661	+3.022	.008	.005	3	2
BLOOD_Leukemia	ACD →	+0.649	+3.321	<.001	.005	3	2
BLOOD_Leukemia	TNFSF8 →	+1.264	+2.672	.001	.001	3	2
LUNG_SCLC	BAIAP2L2 →	+0.641	+2.584	.001	.003	2	3
BLOOD_Leukemia	STAMBPL1 →	+1.279	+2.548	<.001	.006	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 755 associations by consensus.

OR52N5 by NBPF14 expression — PANCREAS

Explore this box plot interactively →