NBPF11

Across TCGA patient cohorts, NBPF11 mutation is significantly associated with the RNA expression of many other genes, with 4,021 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NBPF11-associated genes across cancer lineages are CENPM, PHBP17, and SSTR2. Each is linked with NBPF11 in more than 2 cancer types. Because this analysis shows association rather than direction, both NBPF11-to-partner and partner-to-NBPF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CENPM grouped by NBPF11-low versus NBPF11-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF11→partner) and Y-score (partner→NBPF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CENPM →	+0.503	+1.874	<.001	.002	3	3
BLCA	PHBP17 →	+0.054	+4.825	<.001	.002	3	2
UCEC	SSTR2 →	-0.507	-2.148	.002	.002	3	2
UCEC	PRF1 →	+0.691	+2.021	.001	<.001	3	2
UCEC	RPL23AP82 →	+0.497	+2.247	<.001	<.001	3	2
UCEC	UBE2L3 →	+0.304	+3.162	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,021 associations by consensus.

CENPM by NBPF11 expression — UCEC

Explore this box plot interactively →