NBPF11

Across TCGA pan-cancer cohorts, NBPF11 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of NBPF11’s most consistent transcriptional readouts.

The strongest signal is observed in liver hepatocellular carcinoma (LIHC), where NBPF11 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NBPF11 is over-expressed in tumor, although a few such as KICH and BRCA show the opposite, repressed pattern.

LIHC, KICH, and HNSC are the cancer types where NBPF11 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NBPF11 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LIHC	Male	All	+0.710	<.001	8	view →
KICH	All	All	−0.571	<.001	5	view →
HNSC	All	III,IV	+0.366	.006	5	view →
KIRC	All	All	+0.225	.001	5	view →
BLCA	Female	III,IV	+0.664	.031	4	view →
STAD	All	II,III,IV	+0.428	.012	4	view →
CHOL	All	All	+1.231	.001	3	view →
BRCA	Female	All	−0.182	.029	2	view →
COAD	Male	All	+0.230	.049	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

NBPF11–LIHC

Open the LIHC breakdown →