NBPF11

Across TCGA cell cohorts, NBPF11 mutation is significantly associated with the RNA expression of many other genes, with 5 significant associations in total. STOMACH shows the largest number of these associations.

The most reproducible NBPF11-associated genes across cancer lineages are PRRG3, GPR101, and TMEM235. Each is linked with NBPF11 in more than 1 cancer types. Because this analysis shows association rather than direction, both NBPF11-to-partner and partner-to-NBPF11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, PRRG3 grouped by NBPF11-low versus NBPF11-high in STOMACH.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NBPF11→partner) and Y-score (partner→NBPF11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	PRRG3 →	+0.077	+4.129	<.001	.007	3	1
STOMACH	GPR101 →	+0.010	+4.285	<.001	.007	3	1
STOMACH	TMEM235 →	+0.012	+4.794	<.001	.001	3	1
STOMACH	GSG1L2 →	+0.028	+4.794	<.001	.001	3	1
STOMACH	HMX1 →	+1.074	+4.129	<.001	.007	3	1

Each partner links to its Q-omics profile. Showing the 5 strongest of 5 associations by consensus.

PRRG3 by NBPF11 expression — STOMACH

Explore this box plot interactively →