NBEAP1

Across TCGA pan-cancer cohorts, NBEAP1 RNA is linked to patient survival in 27 of 34 cancer types, making it the most broadly survival-associated NBEAP1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NBEAP1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NBEAP1 expression acts as an unfavorable survival marker, although some lineages such as ACC and LGG show a favorable association.

KIRC, HNSC, and KICH are the cancer types where NBEAP1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Quartile	All	0.559	0.738	<.001	75	view →
HNSC	OS	Quartile	II,III,IV	0.429	0.761	.003	41	view →
KICH	DFS	Median	II,III,IV	0.589	1.000	.006	34	view →
OV	OS	Median	III,IV	0.266	0.357	.003	24	view →
ACC	DFS	Median	IV	0.495	0.066	.001	24	view →
LIHC	OS	Tertile	All	0.645	0.818	.002	22	view →
DLBC	OS	Median	All	0.755	0.964	.021	18	view →
GBM	DFS	Tertile	All	0.187	0.320	.011	18	view →
UVM	OS	Quartile	III,IV	0.265	0.836	.008	17	view →
LGG	OS	Quartile	All	0.938	0.842	.004	17	view →
UCEC	OS	Tertile	All	0.910	0.967	.011	16	view →
READ	OS	Quartile	All	0.621	0.946	.006	12	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 27 lineages.

NBEAP1–KIRC (DFS)

Open the KIRC breakdown →