NBEA

Across TCGA cell cohorts, NBEA RNA expression is significantly associated with the go_rna of many other GO terms, with 3,826 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NBEA-associated GO terms across cancer lineages are Heterochromatin formation, Regulation of intracellular steroid hormone receptor signaling pathway, and Golgi vesicle transport. Each is linked with NBEA in more than 10 cancer types. Because this analysis shows association rather than direction, both NBEA-to-partner and partner-to-NBEA results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Heterochromatin formation grouped by NBEA-low versus NBEA-high in LUNG_SCLC.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NBEA→partner) and Y-score (partner→NBEA) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	Heterochromatin formation →	+0.062	+1.109	.007	.003	3	11
BLOOD_Lymphoma	Regulation of intracellular steroid hormone receptor signaling pathway →	+0.079	+0.998	<.001	<.001	3	10
BREAST	Golgi vesicle transport →	+0.046	+0.836	.006	.006	3	10
UPPER_AERODIGESTIVE_TRACT	Heterochromatin organization →	+0.060	+0.657	.001	.008	3	9
LIVER	Negative regulation of gene expression, epigenetic →	+0.063	+1.484	.002	.009	2	10
LARGE_INTESTINE	Transport along microtubule →	+0.028	+0.564	.002	.007	2	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,826 associations by consensus.

Heterochromatin formation by NBEA expression — LUNG_SCLC

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