NAXE

Across TCGA patient cohorts, NAXE protein abundance is significantly associated with the RNA expression of many other genes, with 17,563 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NAXE-associated genes across cancer lineages are PIGM, NCF2, and BCL2A1. Each is linked with NAXE in more than 7 cancer types. Because this analysis shows association rather than direction, both NAXE-to-partner and partner-to-NAXE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAXE versus PIGM in HNSC, with a Pearson correlation of 0.38.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAXE→partner) and Y-score (partner→NAXE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	PIGM →	+0.728	+0.259	<.001	<.001	3	8
OV	NCF2 →	-1.054	-0.727	<.001	<.001	3	7
COAD	BCL2A1 →	-1.222	-0.372	<.001	<.001	3	7
OV	FPR1 →	-1.273	-0.664	<.001	<.001	3	7
UCEC	ASH1L →	+0.682	+0.460	<.001	<.001	3	7
UCEC	RCOR3 →	+0.786	+0.324	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,563 associations by consensus.

NAXE vs PIGM — HNSC

Explore this scatter interactively →