NAXE

Across TCGA patient cohorts, NAXE protein abundance is significantly associated with the protein abundance of many other proteins, with 21,621 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NAXE-associated proteins across cancer lineages are BROX, SCCPDH, and PRDX6. Each is linked with NAXE in more than 8 cancer types. Because this analysis shows association rather than direction, both NAXE-to-partner and partner-to-NAXE results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAXE versus BROX in OV, with a Pearson correlation of 0.50.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NAXE→partner) and Y-score (partner→NAXE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	BROX →	+0.582	+0.676	<.001	<.001	3	9
HNSC	SCCPDH →	+0.681	+0.342	<.001	<.001	3	9
HNSC	PRDX6 →	+0.391	+0.310	<.001	.001	3	9
LSCC	CYBA →	-0.571	-0.323	<.001	<.001	3	8
LSCC	DARS2 →	+0.536	+0.377	<.001	<.001	3	8
PDAC	FH →	+0.353	+0.342	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 21,621 associations by consensus.

NAXE vs BROX — OV

Explore this scatter interactively →