NAXE

Across TCGA cell cohorts, NAXE RNA expression is significantly associated with the go_rna of many other GO terms, with 4,776 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NAXE-associated GO terms across cancer lineages are Membrane raft distribution, Nucleotide biosynthetic process, and Mitochondrial potassium ion transmembrane transport. Each is linked with NAXE in more than 12 cancer types. Because this analysis shows association rather than direction, both NAXE-to-partner and partner-to-NAXE results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Membrane raft distribution grouped by NAXE-low versus NAXE-high in UPPER_AERODIGESTIVE_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAXE→partner) and Y-score (partner→NAXE) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UPPER_AERODIGESTIVE_TRACT	Membrane raft distribution →	+0.200	+0.662	.009	.005	3	13
BLOOD_Lymphoma	Nucleotide biosynthetic process →	+0.068	+0.772	<.001	.002	3	10
OVARY	Mitochondrial potassium ion transmembrane transport →	+0.117	+0.793	.001	.003	3	10
SKIN	Aminoacyl-tRNA metabolism involved in translational fidelity →	+0.102	+0.883	<.001	<.001	3	10
OESOPHAGUS	Water-soluble vitamin biosynthetic process →	+0.136	+0.782	.003	.001	3	10
PANCREAS	Pyrimidine-containing compound biosynthetic process →	+0.078	+0.633	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,776 associations by consensus.

Membrane raft distribution by NAXE expression — UPPER_AERODIGESTIVE_TRACT

Explore this box plot interactively →