NAV2-AS5

Across TCGA pan-cancer cohorts, NAV2-AS5 RNA is linked to patient survival in 14 of 34 cancer types, making it the most broadly survival-associated NAV2-AS5 data layer.

The strongest signal is observed in rectum adenocarcinoma (READ), where higher NAV2-AS5 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NAV2-AS5 expression acts as an unfavorable survival marker, although some lineages such as LUAD and LAML show a favorable association.

READ, MESO, and BLCA are the cancer types where NAV2-AS5 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
READ	DFS	Tertile	IV	0.168	0.640	<.001	57	view →
MESO	DFS	Tertile	IV	0.112	0.438	<.001	50	view →
BLCA	OS	Tertile	III,IV	0.336	0.600	.016	21	view →
LUAD	DFS	Tertile	II,III,IV	0.837	0.665	.021	21	view →
LAML	DFS	Median	All	0.668	0.476	.013	20	view →
ACC	OS	Tertile	III,IV	1.000	0.326	.034	18	view →
OV	DFS	Tertile	IV	0.331	0.523	.030	12	view →
LIHC	OS	Quartile	III,IV	0.869	0.502	.013	10	view →
SKCM	DFS	Tertile	II,III,IV	0.218	0.593	.038	9	view →
THCA	OS	Quartile	All	0.981	1.000	.005	7	view →
THYM	DFS	Tertile	All	0.236	0.735	.038	6	view →
STAD	DFS	Tertile	IV	0.268	0.546	.040	6	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 14 lineages.

NAV2-AS5–READ (DFS)

Open the READ breakdown →