NAV2-AS5

Across TCGA pan-cancer cohorts, NAV2-AS5 RNA differs between tumor and matched normal tissue in 6 of 18 cancer types tested, making tumor–normal expression one of NAV2-AS5’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where NAV2-AS5 RNA is repressed in tumor relative to normal tissue. In most cancer types NAV2-AS5 is over-expressed in tumor, although a few such as THCA and KIRC show the opposite, repressed pattern.

THCA, KIRC, and LUSC are the cancer types where NAV2-AS5 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NAV2-AS5 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	All	All	−0.153	<.001	9	view →
KIRC	All	II,III,IV	−0.009	<.001	9	view →
LUSC	All	II,III,IV	−0.036	<.001	7	view →
KIRP	All	All	−0.007	.005	5	view →
KICH	Male	All	−0.017	.002	3	view →
CHOL	All	All	−0.037	.001	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 6 strongest of 6 lineages.

NAV2-AS5–THCA

Open the THCA breakdown →