NAV2-AS4

Across TCGA pan-cancer cohorts, NAV2-AS4 RNA is linked to patient survival in 20 of 34 cancer types, making it the most broadly survival-associated NAV2-AS4 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher NAV2-AS4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NAV2-AS4 expression acts as an unfavorable survival marker, although some lineages such as LIHC and ACC show a favorable association.

UCS, LIHC, and CHOL are the cancer types where NAV2-AS4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	OS	Tertile	All	0.450	0.753	.005	60	view →
LIHC	OS	Median	All	0.591	0.415	<.001	57	view →
CHOL	OS	Median	II,III,IV	0.349	0.915	.001	54	view →
ACC	DFS	Tertile	III,IV	0.570	0.106	.009	52	view →
ESCA	OS	Tertile	IV	0.095	0.512	.008	36	view →
LGG	OS	Median	All	0.872	0.750	<.001	36	view →
STAD	DFS	Tertile	IV	0.083	0.379	.001	30	view →
DLBC	OS	Tertile	III,IV	0.272	1.000	.017	22	view →
SARC	OS	Tertile	All	0.820	0.413	.002	22	view →
TGCT	DFS	Tertile	All	0.509	0.731	.006	20	view →
PAAD	DFS	Tertile	III,IV	0.118	0.734	.014	18	view →
LUSC	OS	Tertile	IV	0.001	0.651	.025	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 20 lineages.

NAV2-AS4–UCS (OS)

Open the UCS breakdown →