NAV2-AS3

RNA & survival
SurvivalRNAKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NAV2-AS3 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated NAV2-AS3 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NAV2-AS3 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NAV2-AS3 expression acts as an unfavorable survival marker, although some lineages such as READ and ESCA show a favorable association.

KIRC, KIRP, and ACC are the cancer types where NAV2-AS3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
KIRCOSTertileAll0.5320.658.00161view →
KIRPOSQuartileAll0.7930.915.00434view →
ACCDFSTertileAll0.2180.657.02130view →
STADDFSMedianII,III,IV0.5650.789.00227view →
CESCDFSQuartileII,III,IV0.3240.674.00224view →
LUSCOSQuartileIII,IV0.1410.668.00324view →
READOSTertileIV0.9950.565.01624view →
LUADDFSMedianAll0.2250.452.00516view →
ESCAOSQuartileIII,IV0.6240.319.02114view →
BRCADFSTertileIV0.2750.799.0059view →
CHOLOSQuartileAll0.2960.709.0323view →
LIHCOSTertileAll0.7190.810.0353view →
Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

NAV2-AS3–KIRC (OS)

Kaplan–Meier survival curve for NAV2-AS3 RNA-high vs -low samples in KIRC.

Open the KIRC breakdown →

Exploration