NAV2-AS3

Across TCGA pan-cancer cohorts, NAV2-AS3 RNA differs between tumor and matched normal tissue in 9 of 18 cancer types tested, making tumor–normal expression one of NAV2-AS3’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NAV2-AS3 RNA is repressed in tumor relative to normal tissue. In most cancer types NAV2-AS3 is over-expressed in tumor, although a few such as KIRC and KIRP show the opposite, repressed pattern.

KIRC, BRCA, and BLCA are the cancer types where NAV2-AS3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NAV2-AS3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	Male	II,III,IV	−1.131	<.001	12	view →
BRCA	All	All	+0.228	<.001	6	view →
BLCA	Female	IV	+0.536	.001	4	view →
KIRP	All	All	−0.494	.003	4	view →
ESCA	All	II,III,IV	+0.425	.016	2	view →
UCEC	All	All	−0.339	.010	2	view →
LUAD	All	All	+0.311	.013	2	view →
LIHC	All	All	+0.142	.005	2	view →
READ	All	All	+0.093	.030	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 9 strongest of 9 lineages.

NAV2-AS3–KIRC

Open the KIRC breakdown →