NAV2-AS2

Across TCGA pan-cancer cohorts, NAV2-AS2 RNA is linked to patient survival in 19 of 34 cancer types, making it the most broadly survival-associated NAV2-AS2 data layer.

The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NAV2-AS2 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NAV2-AS2 expression acts as an unfavorable survival marker, although some lineages such as LUAD and PAAD show a favorable association.

LUAD, BLCA, and UVM are the cancer types where NAV2-AS2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LUAD	DFS	Quartile	All	0.750	0.561	<.001	67	view →
BLCA	DFS	Quartile	All	0.190	0.381	<.001	59	view →
UVM	DFS	Tertile	All	0.320	0.887	<.001	44	view →
MESO	OS	Tertile	All	0.202	0.407	.006	29	view →
KIRP	DFS	Quartile	All	0.806	0.940	<.001	29	view →
SKCM	OS	Tertile	IV	0.312	0.814	.004	26	view →
KICH	DFS	Median	III,IV	0.341	0.853	.008	23	view →
PAAD	DFS	Tertile	All	0.461	0.275	.007	21	view →
HNSC	OS	Median	IV	0.460	0.281	.005	20	view →
THCA	DFS	Tertile	All	0.959	0.876	.001	20	view →
CHOL	OS	Tertile	II,III,IV	0.024	0.601	.025	18	view →
ACC	OS	Quartile	II,III,IV	0.716	0.883	.008	18	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 19 lineages.

NAV2-AS2–LUAD (DFS)

Open the LUAD breakdown →