NAV1

Across TCGA cell cohorts, NAV1 mutation is significantly associated with the RNA expression of many other genes, with 2,575 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAV1-associated genes across cancer lineages are SLC38A8, OR2C1, and PPP6R2. Each is linked with NAV1 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAV1-to-partner and partner-to-NAV1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SLC38A8 grouped by NAV1-low versus NAV1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAV1→partner) and Y-score (partner→NAV1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	SLC38A8 →	+0.045	+3.606	.009	.002	3	2
OVARY	OR2C1 →	+0.034	+3.544	.003	.004	3	2
LARGE_INTESTINE	PPP6R2 →	+0.577	+3.459	.001	<.001	3	2
LARGE_INTESTINE	ARSA →	+0.638	+2.459	<.001	.006	3	2
LARGE_INTESTINE	CCDC113 →	+0.801	+3.526	<.001	<.001	3	2
LARGE_INTESTINE	CLUAP1 →	+0.524	+1.800	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,575 associations by consensus.

SLC38A8 by NAV1 expression — BLOOD_Lymphoma

Explore this box plot interactively →