Across TCGA pan-cancer cohorts, NATD1 mass-spec protein is linked to patient survival in 1 of 34 cancer types, making it a survival-associated NATD1 data layer compared with 25 for mass-spec protein and 2 for mutation status.
The strongest signal is observed in lung adenocarcinoma (LUAD), where higher NATD1 mass-spec protein is associated with better overall survival. In most high-consensus cancer types, elevated NATD1 expression acts as an unfavorable survival marker, although some lineages such as LUAD show a favorable association.
LUAD are the cancer types where NATD1 mass-spec protein most reproducibly stratifies survival.