NATD1

Across TCGA pan-cancer cohorts, NATD1 RNA differs between tumor and matched normal tissue in 12 of 18 cancer types tested, making tumor–normal expression one of NATD1’s most consistent transcriptional readouts.

The strongest signal is observed in lung adenocarcinoma (LUAD), where NATD1 RNA is repressed in tumor relative to normal tissue. In most cancer types NATD1 is over-expressed in tumor, although a few such as LUAD and THCA show the opposite, repressed pattern.

LUAD, THCA, and KICH are the cancer types where NATD1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NATD1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
LUAD	Female	III,IV	−1.329	<.001	9	view →
THCA	All	III,IV	−0.696	<.001	9	view →
KICH	Male	All	−1.269	<.001	7	view →
LUSC	Male	All	−1.267	<.001	7	view →
LIHC	All	II,III,IV	+0.766	<.001	7	view →
BRCA	All	III,IV	−1.525	<.001	6	view →
UCEC	All	All	−1.146	<.001	6	view →
KIRC	Male	II,III,IV	−0.541	<.001	6	view →
HNSC	Male	All	−0.641	.005	4	view →
CHOL	Female	All	+2.636	<.001	3	view →
READ	All	All	−0.696	.019	2	view →
PAAD	All	All	−0.692	.034	2	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 12 strongest of 12 lineages.

NATD1–LUAD

Open the LUAD breakdown →