NATD1

Across TCGA patient cohorts, NATD1 mutation is significantly associated with the RNA expression of many other genes, with 254 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NATD1-associated genes across cancer lineages are RNA5SP419, GNPNAT1, and NDUFAF5. Each is linked with NATD1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NATD1-to-partner and partner-to-NATD1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA5SP419 grouped by NATD1-low versus NATD1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NATD1→partner) and Y-score (partner→NATD1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	RNA5SP419 →	+0.632	+2.398	.001	.007	3	2
UCEC	GNPNAT1 →	+0.753	+3.201	.004	.009	3	1
UCEC	NDUFAF5 →	+0.388	+3.660	.006	.001	3	1
UCEC	ATG4A →	+0.547	+3.370	.002	.004	3	1
UCEC	LACTB →	+0.518	+3.627	.004	.001	3	1
UCEC	DOT1L →	+0.709	+3.338	<.001	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 254 associations by consensus.

RNA5SP419 by NATD1 expression — UCEC

Explore this box plot interactively →