NAT9

Across TCGA patient cohorts, NAT9 mutation is significantly associated with the RNA expression of many other genes, with 51 significant associations in total. BLCA shows the largest number of these associations.

The most reproducible NAT9-associated genes across cancer lineages are TP73-AS2, ATP6V0CP2, and CFTRP3. Each is linked with NAT9 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAT9-to-partner and partner-to-NAT9 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP73-AS2 grouped by NAT9-low versus NAT9-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT9→partner) and Y-score (partner→NAT9) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TP73-AS2 →	+0.202	+4.628	<.001	.004	3	2
SKCM	ATP6V0CP2 →	+0.253	+4.953	<.001	.002	3	2
LUAD	CFTRP3 →	+0.263	+7.930	<.001	.008	3	2
BRCA	MIR1277 →	+0.305	+4.800	<.001	.006	3	2
BLCA	USP29 →	+0.016	+4.268	<.001	.008	3	1
BLCA	RNA5SP453 →	+0.453	+4.497	<.001	.009	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 51 associations by consensus.

TP73-AS2 by NAT9 expression — SKCM

Explore this box plot interactively →