Across TCGA cell cohorts, NAT8L RNA expression is significantly associated with the go_rna of many other GO terms, with 5,118 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NAT8L-associated GO terms across cancer lineages are tRNA transcription, Positive regulation of monoatomic ion transport, and tRNA aminoacylation for protein translation. Each is linked with NAT8L in more than 14 cancer types. Because this analysis shows association rather than direction, both NAT8L-to-partner and partner-to-NAT8L results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT8L→partner) and Y-score (partner→NAT8L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	tRNA transcription →	+0.129	+1.764	.009	.003	3	15
LARGE_INTESTINE	Positive regulation of monoatomic ion transport →	-0.100	-1.477	<.001	<.001	3	14
URINARY_TRACT	tRNA aminoacylation for protein translation →	+0.093	+1.471	.002	.003	2	14
BONE	tRNA transcription by RNA polymerase III →	+0.094	+1.665	.008	<.001	2	13
UPPER_AERODIGESTIVE_TRACT	Positive regulation of DNA repair →	+0.076	+1.328	<.001	<.001	3	12
BONE	Positive regulation of transcription by RNA polymerase I →	+0.118	+1.166	<.001	.003	3	12

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,118 associations by consensus.

Exploration

NAT8L survival (RNA) · tumor vs normal (RNA) · all NAT8L data types