NAT16

Across TCGA cell cohorts, NAT16 mutation is significantly associated with the RNA expression of many other genes, with 10 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NAT16-associated genes across cancer lineages are C1QTNF7, EPPIN, and ACTRT1. Each is linked with NAT16 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAT16-to-partner and partner-to-NAT16 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, C1QTNF7 grouped by NAT16-low versus NAT16-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT16→partner) and Y-score (partner→NAT16) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C1QTNF7 →	+0.098	+4.108	<.001	.008	3	1
BLOOD_Leukemia	EPPIN →	+0.006	+4.922	.005	.009	3	1
BLOOD_Leukemia	ACTRT1 →	+0.038	+5.201	<.001	.006	3	1
BLOOD_Leukemia	TRIM42 →	+0.006	+4.922	<.001	.009	3	1
BLOOD_Leukemia	ACTRT2 →	+0.064	+4.922	.001	.009	3	1
BLOOD_Leukemia	MC2R →	+0.006	+5.969	<.001	.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

C1QTNF7 by NAT16 expression — LARGE_INTESTINE

Explore this box plot interactively →