NAT14

Across TCGA patient cohorts, NAT14 protein abundance is significantly associated with the RNA expression of many other genes, with 7,086 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NAT14-associated genes across cancer lineages are TNFSF11, LGALS1, and CNN3. Each is linked with NAT14 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAT14-to-partner and partner-to-NAT14 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NAT14 versus TNFSF11 in HNSC, with a Pearson correlation of 0.41.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT14→partner) and Y-score (partner→NAT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
HNSC	TNFSF11 →	+0.794	+0.460	.001	.003	3	3
LSCC	LGALS1 →	+0.813	+0.292	<.001	.005	3	2
LSCC	CNN3 →	+0.572	+0.321	<.001	<.001	3	2
LSCC	GPR75 →	-0.445	-0.295	.003	.002	3	2
CCRCC	TGFBI →	+1.250	+0.289	.004	.007	3	2
LSCC	PDZRN3 →	+0.782	+0.351	<.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 7,086 associations by consensus.

NAT14 vs TNFSF11 — HNSC

Explore this scatter interactively →