NAT14

Across TCGA cell cohorts, NAT14 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,380 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAT14-associated GO terms across cancer lineages are AMPA glutamate receptor clustering, Glutamate receptor clustering, and Regulation of base-excision repair. Each is linked with NAT14 in more than 10 cancer types. Because this analysis shows association rather than direction, both NAT14-to-partner and partner-to-NAT14 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, AMPA glutamate receptor clustering grouped by NAT14-low versus NAT14-high in URINARY_TRACT.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAT14→partner) and Y-score (partner→NAT14) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
URINARY_TRACT	AMPA glutamate receptor clustering →	+1.231	+1.212	<.001	<.001	3	11
URINARY_TRACT	Glutamate receptor clustering →	+1.231	+1.212	<.001	<.001	3	11
STOMACH	Regulation of base-excision repair →	+0.200	+1.927	<.001	<.001	3	10
LUNG_NSCLC_LUSC	Calcium-independent cell-matrix adhesion →	+0.192	+1.468	.003	<.001	3	9
UPPER_AERODIGESTIVE_TRACT	Negative regulation of myoblast fusion →	+0.138	+0.964	<.001	<.001	3	9
STOMACH	Negative regulation of interferon-alpha production →	+1.205	+1.185	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,380 associations by consensus.

AMPA glutamate receptor clustering by NAT14 expression — URINARY_TRACT

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