NASP

Across TCGA cell cohorts, NASP RNA expression is significantly associated with the go_rna of many other GO terms, with 5,611 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NASP-associated GO terms across cancer lineages are Negative regulation of G2/M transition of mitotic cell cycle, Negative regulation of cell cycle G2/M phase transition, and DNA integrity checkpoint signaling. Each is linked with NASP in more than 18 cancer types. Because this analysis shows association rather than direction, both NASP-to-partner and partner-to-NASP results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of G2/M transition of mitotic cell cycle grouped by NASP-low versus NASP-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NASP→partner) and Y-score (partner→NASP) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Negative regulation of G2/M transition of mitotic cell cycle →	+0.107	+1.496	<.001	.001	3	19
PANCREAS	Negative regulation of cell cycle G2/M phase transition →	+0.091	+1.014	<.001	<.001	3	19
BONE	DNA integrity checkpoint signaling →	+0.099	+1.100	.001	.008	3	19
BONE	Mitotic DNA replication checkpoint signaling →	+0.251	+1.482	<.001	<.001	3	19
OESOPHAGUS	DNA-templated DNA replication maintenance of fidelity →	+0.115	+0.734	.001	.002	3	19
SOFT_TISSUE	Negative regulation of DNA repair →	+0.086	+1.088	<.001	<.001	3	19

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,611 associations by consensus.

Negative regulation of G2/M transition of mitotic cell cycle by NASP expression — BONE

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