NARS1

Across TCGA cell cohorts, NARS1 mutation is significantly associated with the RNA expression of many other genes, with 3 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NARS1-associated genes across cancer lineages are DEFB103A, DEFB103B, and DYNAP. Each is linked with NARS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NARS1-to-partner and partner-to-NARS1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DEFB103A grouped by NARS1-low versus NARS1-high in BLOOD_Lymphoma.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NARS1→partner) and Y-score (partner→NARS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	DEFB103A →	+0.019	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	DEFB103B →	+0.019	+5.209	<.001	.005	3	1
BLOOD_Lymphoma	DYNAP →	+0.071	+4.867	.002	.009	3	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

DEFB103A by NARS1 expression — BLOOD_Lymphoma

Explore this box plot interactively →