NAPG

Across TCGA cell cohorts, NAPG mutation is significantly associated with the RNA expression of many other genes, with 11 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAPG-associated genes across cancer lineages are POTEB2, CRTAM, and OPN5. Each is linked with NAPG in more than 1 cancer types. Because this analysis shows association rather than direction, both NAPG-to-partner and partner-to-NAPG results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, POTEB2 grouped by NAPG-low versus NAPG-high in LUNG_SCLC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAPG→partner) and Y-score (partner→NAPG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	POTEB2 →	+0.012	+5.029	<.001	.006	3	1
LARGE_INTESTINE	CRTAM →	+0.471	+3.006	.001	.006	3	1
LARGE_INTESTINE	OPN5 →	+0.019	+3.115	.002	.004	3	1
LARGE_INTESTINE	OR14K1 →	+0.058	+3.700	<.001	.009	3	1
LARGE_INTESTINE	TCERG1L →	+0.066	+3.584	.005	.006	3	1
LARGE_INTESTINE	NPY2R →	+0.003	+3.217	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 11 associations by consensus.

POTEB2 by NAPG expression — LUNG_SCLC

Explore this box plot interactively →