NAP1L5

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NAP1L5 mutation is significantly associated with the RNA expression of many other genes, with 2,109 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAP1L5-associated genes across cancer lineages are RN7SL248P, RNU4-88P, and RNA5SP419. Each is linked with NAP1L5 in more than 2 cancer types. Because this analysis shows association rather than direction, both NAP1L5-to-partner and partner-to-NAP1L5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RN7SL248P grouped by NAP1L5-low versus NAP1L5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAP1L5→partner) and Y-score (partner→NAP1L5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECRN7SL248P →+0.066+3.307<.001.00333
BLCARNU4-88P →+0.378+7.640<.001.00932
UCECRNA5SP419 →+0.612+2.299<.001.00132
UCECLAMTOR1 →+0.334+2.425.009.00231
UCECGRIK4 →-0.466-3.087.005<.00131
UCECTMEM138 →+0.346+3.711<.001<.00131
Each partner links to its Q-omics profile. Showing the 6 strongest of 2,109 associations by consensus.

RN7SL248P by NAP1L5 expression — UCEC

Box plot of RN7SL248P in NAP1L5-low vs NAP1L5-high samples in UCEC.

Explore this box plot interactively →

Exploration