Across TCGA patient cohorts, NANOS2 mutation is significantly associated with the RNA expression of many other genes, with 44 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NANOS2-associated genes across cancer lineages are RPL35AP30, CTDSPL2P1, and MRPL50P2. Each is linked with NANOS2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NANOS2-to-partner and partner-to-NANOS2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOS2→partner) and Y-score (partner→NANOS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	RPL35AP30 →	+0.362	+4.126	<.001	.004	3	1
COAD	CTDSPL2P1 →	+0.117	+4.463	.004	.002	3	1
COAD	MRPL50P2 →	+0.412	+4.042	<.001	.005	3	1
COAD	ZNF736P7Y →	+0.068	+4.666	<.001	.005	3	1
COAD	AGGF1P9 →	+0.097	+4.666	<.001	.005	3	1
COAD	IGLJCOR18 →	+0.446	+4.338	<.001	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 44 associations by consensus.

Exploration

NANOS2 survival (RNA) · tumor vs normal (RNA) · all NANOS2 data types