Across TCGA cell cohorts, NANOS2 RNA expression is significantly associated with the go_rna of many other GO terms, with 664 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible NANOS2-associated GO terms across cancer lineages are Calcium ion transport, Regulation of the force of skeletal muscle contraction, and Regulation of skeletal muscle contraction by chemo-mechanical energy conversion. Each is linked with NANOS2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NANOS2-to-partner and partner-to-NANOS2 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOS2→partner) and Y-score (partner→NANOS2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	Calcium ion transport →	-0.046	-0.021	<.001	.002	3	4
LUNG_NSCLC_LUAD	Regulation of the force of skeletal muscle contraction →	+0.121	+0.013	<.001	.008	3	4
LUNG_NSCLC_LUAD	Regulation of skeletal muscle contraction by chemo-mechanical energy conversion →	+0.121	+0.013	<.001	.008	3	4
LUNG_NSCLC_LUAD	Positive regulation of matrix metallopeptidase secretion →	+0.135	+0.015	.003	.007	3	4
OVARY	Negative regulation of transcription elongation by RNA polymerase II →	+0.100	+0.027	<.001	.008	2	5
LUNG_NSCLC_LUAD	Liver regeneration →	+0.065	+0.010	.005	.003	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 664 associations by consensus.

Exploration

NANOS2 survival (RNA) · tumor vs normal (RNA) · all NANOS2 data types