NANOS1

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NANOS1 mutation is significantly associated with the RNA expression of many other genes, with 508 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NANOS1-associated genes across cancer lineages are RNA5SP139, RN7SL470P, and RNU6-1064P. Each is linked with NANOS1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NANOS1-to-partner and partner-to-NANOS1 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOS1→partner) and Y-score (partner→NANOS1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIRPRNA5SP139 →+0.479+5.264<.001.00632
UCECRN7SL470P →+0.189+2.109.005.00832
UCECRNU6-1064P →+0.814+2.739<.001<.00132
UCECVTRNA2-2P →+0.443+2.204<.001.00632
LIHCNPAP1L →+0.044+5.676.005.00131
KIRPRNA5SP146 →+0.272+5.264<.001.00631
Each partner links to its Q-omics profile. Showing the 6 strongest of 508 associations by consensus.

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