NANOGP8

Across TCGA pan-cancer cohorts, NANOGP8 RNA is linked to patient survival in 17 of 34 cancer types, making it the most broadly survival-associated NANOGP8 data layer.

The strongest signal is observed in thyroid carcinoma (THCA), where higher NANOGP8 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NANOGP8 expression acts as an unfavorable survival marker, although some lineages such as LIHC and BRCA show a favorable association.

THCA, COAD, and UVM are the cancer types where NANOGP8 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
THCA	DFS	Tertile	II,III,IV	0.576	0.824	<.001	132	view →
COAD	OS	Tertile	II,III,IV	0.345	0.642	<.001	57	view →
UVM	OS	Quartile	All	0.681	0.980	.020	39	view →
LIHC	OS	Tertile	II,III,IV	0.847	0.663	.003	38	view →
UCEC	DFS	Tertile	IV	0.358	0.782	.007	24	view →
BRCA	OS	Tertile	III,IV	0.916	0.784	.009	18	view →
KIRP	DFS	Quartile	II,III,IV	1.000	0.380	.011	18	view →
SKCM	OS	Median	IV	0.867	0.225	.001	14	view →
ACC	OS	Median	IV	0.908	0.523	.013	10	view →
LUAD	DFS	Tertile	II,III,IV	0.588	0.779	.005	10	view →
PAAD	DFS	Tertile	III,IV	0.152	0.821	.045	9	view →
PRAD	OS	Tertile	All	0.784	0.973	.006	8	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 17 lineages.

NANOGP8–THCA (DFS)

Open the THCA breakdown →