NANOGP2

Across TCGA patient cohorts, NANOGP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 6,495 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NANOGP2-associated GO terms across cancer lineages are Regulation of mRNA processing, Regulation of mRNA splicing, via spliceosome, and RNA 3'-end processing. Each is linked with NANOGP2 in more than 14 cancer types. Because this analysis shows association rather than direction, both NANOGP2-to-partner and partner-to-NANOGP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by NANOGP2-low versus NANOGP2-high in ESCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NANOGP2→partner) and Y-score (partner→NANOGP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
ESCA	Regulation of mRNA processing →	+0.064	+0.231	.001	<.001	3	15
STAD	Regulation of mRNA splicing, via spliceosome →	+0.058	+0.203	<.001	<.001	3	14
STAD	RNA 3'-end processing →	+0.049	+0.174	<.001	<.001	3	14
STAD	Regulation of mRNA catabolic process →	+0.037	+0.159	<.001	<.001	3	13
STAD	Obsolete ncRNA transcription →	+0.044	+0.163	<.001	<.001	3	13
DLBC	Positive regulation of translation →	+0.051	+0.135	.001	.002	3	13

Each partner links to its Q-omics profile. Showing the 6 strongest of 6,495 associations by consensus.

Regulation of mRNA processing by NANOGP2 expression — ESCA

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