NANOGP2

Across TCGA pan-cancer cohorts, NANOGP2 RNA is linked to patient survival in 11 of 34 cancer types, making it the most broadly survival-associated NANOGP2 data layer.

The strongest signal is observed in lymphoid neoplasm diffuse large b-cell lymphoma (DLBC), where higher NANOGP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NANOGP2 expression acts as an unfavorable survival marker, although some lineages such as LUSC and BLCA show a favorable association.

DLBC, THYM, and UCEC are the cancer types where NANOGP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
DLBC	OS	Tertile	II,III,IV	0.257	1.000	<.001	106	view →
THYM	OS	Tertile	All	0.577	0.917	<.001	96	view →
UCEC	DFS	Tertile	All	0.476	0.673	<.001	84	view →
COAD	OS	Tertile	III,IV	0.509	0.817	<.001	72	view →
READ	OS	Tertile	All	0.706	0.921	.008	27	view →
LUSC	OS	Quartile	III,IV	0.854	0.618	.008	25	view →
PAAD	DFS	Quartile	All	0.160	0.328	.020	24	view →
BLCA	DFS	Tertile	All	0.854	0.547	.024	18	view →
KIRC	OS	Quartile	II,III,IV	0.420	0.561	.033	8	view →
STAD	OS	Quartile	III,IV	0.511	0.252	.001	7	view →
ESCA	OS	Tertile	IV	0.243	0.743	.024	6	view →

Pink = unfavorable, green = favorable. Showing the 11 strongest of 11 lineages.

NANOGP2–DLBC (OS)

Open the DLBC breakdown →