NAMPTP3

Across TCGA pan-cancer cohorts, NAMPTP3 RNA is linked to patient survival in 15 of 34 cancer types, making it the most broadly survival-associated NAMPTP3 data layer.

The strongest signal is observed in uterine carcinosarcoma (UCS), where higher NAMPTP3 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NAMPTP3 expression acts as an unfavorable survival marker, although some lineages such as COAD and STAD show a favorable association.

UCS, PAAD, and SKCM are the cancer types where NAMPTP3 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCS	DFS	Tertile	III,IV	0.157	0.460	.016	72	view →
PAAD	DFS	Tertile	II,III,IV	0.243	0.507	<.001	54	view →
SKCM	DFS	Tertile	III,IV	0.355	0.651	<.001	36	view →
THYM	OS	Tertile	All	0.169	0.930	<.001	36	view →
KIRP	DFS	Tertile	II,III,IV	0.489	0.826	.002	27	view →
LGG	OS	Tertile	All	0.770	0.910	<.001	27	view →
CHOL	OS	Tertile	All	0.089	0.673	.018	18	view →
COAD	OS	Tertile	II,III,IV	1.000	0.829	.013	18	view →
STAD	DFS	Tertile	IV	0.621	0.212	.045	9	view →
THCA	OS	Tertile	III,IV	0.335	0.931	.007	9	view →
HNSC	DFS	Tertile	III,IV	0.194	0.366	.035	9	view →
READ	OS	Tertile	All	1.000	0.890	.033	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 15 lineages.

NAMPTP3–UCS (DFS)

Open the UCS breakdown →