NAMPTP3

Across TCGA pan-cancer cohorts, NAMPTP3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NAMPTP3’s most consistent transcriptional readouts.

The strongest signal is observed in head and neck squamous cell carcinoma (HNSC), where NAMPTP3 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NAMPTP3 is over-expressed in tumor, although a few such as LIHC and KICH show the opposite, repressed pattern.

HNSC, COAD, and LIHC are the cancer types where NAMPTP3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NAMPTP3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
HNSC	All	II,III,IV	+0.093	.039	2	view →
COAD	All	II,III,IV	+0.121	.038	1	view →
LIHC	Male	All	−0.114	.010	1	view →
KICH	All	II,III,IV	−0.080	.033	1	view →
KIRP	All	All	+0.070	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NAMPTP3–HNSC

Open the HNSC breakdown →