NAMPTP2

Across TCGA patient cohorts, NAMPTP2 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,242 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NAMPTP2-associated GO terms across cancer lineages are Regulation of protein localization to membrane, Regulation of ubiquitin-dependent protein catabolic process, and Protein targeting to membrane. Each is linked with NAMPTP2 in more than 5 cancer types. Because this analysis shows association rather than direction, both NAMPTP2-to-partner and partner-to-NAMPTP2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of protein localization to membrane grouped by NAMPTP2-low versus NAMPTP2-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NAMPTP2→partner) and Y-score (partner→NAMPTP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Regulation of protein localization to membrane →	+0.094	+0.031	<.001	.006	3	6
STAD	Regulation of ubiquitin-dependent protein catabolic process →	+0.114	+0.040	<.001	.001	3	6
STAD	Protein targeting to membrane →	+0.104	+0.034	<.001	.004	3	6
STAD	Obsolete selective autophagy →	+0.103	+0.028	<.001	.004	3	5
STAD	Morphogenesis of embryonic epithelium →	+0.080	+0.020	<.001	.002	3	5
STAD	Response to reactive oxygen species →	+0.108	+0.037	<.001	.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,242 associations by consensus.

Regulation of protein localization to membrane by NAMPTP2 expression — STAD

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