NAMPTP2

Across TCGA pan-cancer cohorts, NAMPTP2 RNA is linked to patient survival in 6 of 34 cancer types, making it the most broadly survival-associated NAMPTP2 data layer.

The strongest signal is observed in brain lower grade glioma (LGG), where higher NAMPTP2 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NAMPTP2 expression acts as an unfavorable survival marker, although some lineages such as OV show a favorable association.

LGG, CESC, and OV are the cancer types where NAMPTP2 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
LGG	OS	Tertile	All	0.155	0.451	<.001	39	view →
CESC	OS	Tertile	III,IV	0.068	0.756	<.001	36	view →
OV	OS	Tertile	III,IV	1.000	0.676	.023	36	view →
SARC	DFS	Tertile	All	0.304	0.619	.004	27	view →
READ	OS	Tertile	All	0.575	0.832	.015	24	view →
KIRP	DFS	Tertile	II,III,IV	0.188	0.693	.030	18	view →

Pink = unfavorable, green = favorable. Showing the 6 strongest of 6 lineages.

NAMPTP2–LGG (OS)

Open the LGG breakdown →