NAIPP4

Across TCGA pan-cancer cohorts, NAIPP4 RNA is linked to patient survival in 21 of 34 cancer types, making it the most broadly survival-associated NAIPP4 data layer.

The strongest signal is observed in adrenocortical carcinoma (ACC), where higher NAIPP4 RNA is associated with worse overall survival. In most high-consensus cancer types, elevated NAIPP4 expression acts as an unfavorable survival marker, although some lineages such as SKCM and PAAD show a favorable association.

ACC, SKCM, and LGG are the cancer types where NAIPP4 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
ACC	OS	Tertile	IV	0.342	0.929	.001	55	view →
SKCM	OS	Median	III,IV	0.804	0.593	.001	46	view →
LGG	DFS	Median	All	0.667	0.797	<.001	43	view →
LIHC	DFS	Tertile	II,III,IV	0.224	0.469	<.001	38	view →
KIRC	DFS	Tertile	II,III,IV	0.432	0.670	.008	21	view →
DLBC	DFS	Median	All	0.611	0.886	.016	18	view →
PAAD	DFS	Quartile	All	0.472	0.263	.005	15	view →
GBM	DFS	Median	All	0.382	0.191	.004	14	view →
ESCA	OS	Tertile	IV	0.373	0.916	.024	12	view →
UCS	DFS	Tertile	IV	0.857	0.361	.024	12	view →
MESO	DFS	Tertile	III,IV	0.297	0.489	.025	12	view →
LAML	DFS	Tertile	All	0.576	0.321	.018	10	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 21 lineages.

NAIPP4–ACC (OS)

Open the ACC breakdown →