NAIPP4

Across TCGA pan-cancer cohorts, NAIPP4 RNA differs between tumor and matched normal tissue in 7 of 18 cancer types tested, making tumor–normal expression one of NAIPP4’s most consistent transcriptional readouts.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where NAIPP4 RNA is repressed in tumor relative to normal tissue. In most cancer types NAIPP4 is over-expressed in tumor, although a few such as UCEC and THCA show the opposite, repressed pattern.

UCEC, THCA, and LIHC are the cancer types where NAIPP4 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NAIPP4 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
UCEC	All	All	−0.265	<.001	8	view →
THCA	Male	All	−0.367	<.001	6	view →
LIHC	Female	All	+0.152	<.001	5	view →
CHOL	All	All	+0.557	<.001	3	view →
LUSC	All	All	−0.120	.009	2	view →
KIRC	All	All	+0.078	.023	2	view →
KICH	All	All	−0.103	.034	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 7 strongest of 7 lineages.

NAIPP4–UCEC

Open the UCEC breakdown →