NAIF1

Across TCGA pan-cancer cohorts, NAIF1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NAIF1 data layer compared with 18 for mass-spec protein and 3 for mutation status.

The strongest signal is observed in clear cell renal cell carcinoma (CCRCC), where higher NAIF1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NAIF1 expression acts as an unfavorable survival marker, although some lineages such as CCRCC and HNSC show a favorable association.

CCRCC, HNSC, and LUAD are the cancer types where NAIF1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CCRCC	DFS	Median	All	1.000	0.542	.017	7	view →
HNSC	DFS	Quartile	II,III,IV	0.934	0.614	.020	7	view →
LUAD	DFS	Quartile	All	1.000	0.423	.016	5	view →
UCEC	DFS	Median	II,III,IV	0.398	1.000	.040	4	view →
LSCC	OS	Median	III,IV	0.840	0.474	.031	4	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NAIF1–CCRCC (DFS)

Open the CCRCC breakdown →