NAIF1

Across TCGA patient cohorts, NAIF1 mutation is significantly associated with the total protein of many other genes, with 8 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAIF1-associated genes across cancer lineages are p90 RSK, PRDX1, and Rictor_pT1135. Each is linked with NAIF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAIF1-to-partner and partner-to-NAIF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, p90 RSK grouped by NAIF1-low versus NAIF1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAIF1→partner) and Y-score (partner→NAIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	p90 RSK →	+0.229	+3.598	.013	.001	3	1
UCEC	PRDX1 →	+0.317	+3.169	.001	.018	3	1
UCEC	Rictor_pT1135 →	-0.135	-2.459	.006	.020	3	1
UCEC	STAT5a →	+0.440	+2.999	.022	.035	3	1
UCEC	Bax →	+0.231	+2.179	.046	.034	3	1
UCEC	Cyclin-B1 →	+0.646	+3.169	.017	.018	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 8 associations by consensus.

p90 RSK by NAIF1 expression — UCEC

Explore this box plot interactively →