NAIF1

Across TCGA cell cohorts, NAIF1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NAIF1-associated genes across cancer lineages are OR10R2, ZNF831, and TAFA1. Each is linked with NAIF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAIF1-to-partner and partner-to-NAIF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR10R2 grouped by NAIF1-low versus NAIF1-high in BLOOD_Leukemia.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAIF1→partner) and Y-score (partner→NAIF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Leukemia	OR10R2 →	+1.283	+4.551	.006	.004	3	1
LARGE_INTESTINE	ZNF831 →	+0.018	+4.273	<.001	.006	3	1
LARGE_INTESTINE	TAFA1 →	+0.410	+4.273	<.001	.006	3	1
LARGE_INTESTINE	CENPVL1 →	+0.227	+4.095	<.001	.009	3	1
BLOOD_Lymphoma	OR5A1 →	+0.015	+5.209	.008	.005	3	1
BLOOD_Lymphoma	USP17L17 →	+0.023	+6.247	<.001	<.001	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

OR10R2 by NAIF1 expression — BLOOD_Leukemia

Explore this box plot interactively →