NAGK

Across TCGA patient cohorts, NAGK mutation is significantly associated with the RNA expression of many other genes, with 1,783 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAGK-associated genes across cancer lineages are OR56A7P, WBP1LP7, and RNA5SP139. Each is linked with NAGK in more than 1 cancer types. Because this analysis shows association rather than direction, both NAGK-to-partner and partner-to-NAGK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, OR56A7P grouped by NAGK-low versus NAGK-high in BLCA.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAGK→partner) and Y-score (partner→NAGK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLCA	OR56A7P →	+0.115	+5.038	<.001	.009	3	2
BRCA	WBP1LP7 →	+0.099	+9.057	<.001	.003	3	2
LUAD	RNA5SP139 →	+0.776	+3.875	<.001	.004	3	2
LUAD	SOD1P1 →	+0.182	+4.533	<.001	<.001	3	2
LUAD	MTATP6P7 →	+0.037	+4.912	<.001	.003	3	2
LUAD	LINC01987 →	+0.156	+4.076	<.001	.002	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,783 associations by consensus.

OR56A7P by NAGK expression — BLCA

Explore this box plot interactively →