NAF1

Across TCGA patient cohorts, NAF1 mutation is significantly associated with the RNA expression of many other genes, with 2,229 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NAF1-associated genes across cancer lineages are LINC01159, SNX18P23, and RN7SL62P. Each is linked with NAF1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NAF1-to-partner and partner-to-NAF1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LINC01159 grouped by NAF1-low versus NAF1-high in READ.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NAF1→partner) and Y-score (partner→NAF1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
READ	LINC01159 →	+0.029	+4.827	<.001	.002	3	2
READ	SNX18P23 →	+0.057	+4.653	<.001	.007	3	2
CESC	RN7SL62P →	+0.152	+5.812	<.001	.003	3	2
CESC	IGHVIV-44-1 →	+0.248	+5.201	<.001	.007	3	2
CESC	RN7SL66P →	+0.158	+5.010	<.001	.009	3	2
CESC	CDRT15P7 →	+0.078	+5.669	<.001	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,229 associations by consensus.

LINC01159 by NAF1 expression — READ

Explore this box plot interactively →