NADK2-AS1

Across TCGA pan-cancer cohorts, NADK2-AS1 RNA is linked to patient survival in 24 of 34 cancer types, making it the most broadly survival-associated NADK2-AS1 data layer.

The strongest signal is observed in cervical squamous cell carcinoma and endocervical adenocarcinoma (CESC), where higher NADK2-AS1 RNA is associated with worse disease-free survival. In most high-consensus cancer types, elevated NADK2-AS1 expression acts as an unfavorable survival marker, although some lineages such as READ and HNSC show a favorable association.

CESC, UCEC, and KICH are the cancer types where NADK2-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
CESC	DFS	Median	All	0.659	0.825	<.001	76	view →
UCEC	DFS	Median	All	0.603	0.671	<.001	64	view →
KICH	DFS	Median	II,III,IV	0.660	1.000	<.001	55	view →
READ	OS	Median	All	0.778	0.310	<.001	51	view →
HNSC	DFS	Quartile	IV	0.750	0.407	.006	44	view →
LGG	DFS	Median	All	0.788	0.877	.001	34	view →
MESO	OS	Quartile	All	0.246	0.467	.010	33	view →
UCS	DFS	Median	IV	0.952	0.367	.001	30	view →
LAML	DFS	Quartile	All	0.622	0.303	.004	30	view →
UVM	DFS	Median	III,IV	0.208	0.740	.006	28	view →
BRCA	DFS	Tertile	III,IV	0.938	0.809	.008	23	view →
ESCA	OS	Tertile	III,IV	0.672	0.337	.006	20	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 24 lineages.

NADK2-AS1–CESC (DFS)

Open the CESC breakdown →