NADK2-AS1

Across TCGA pan-cancer cohorts, NADK2-AS1 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NADK2-AS1’s most consistent transcriptional readouts.

The strongest signal is observed in thyroid carcinoma (THCA), where NADK2-AS1 RNA is repressed in tumor relative to normal tissue. In most cancer types NADK2-AS1 is over-expressed in tumor, although a few such as THCA and CHOL show the opposite, repressed pattern.

THCA, HNSC, and CHOL are the cancer types where NADK2-AS1 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NADK2-AS1 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
THCA	Female	All	−0.637	<.001	5	view →
HNSC	All	III,IV	+0.244	.006	5	view →
CHOL	Male	All	−0.840	.019	2	view →
KIRP	All	IV	+0.550	.001	2	view →
KIRC	Male	All	+0.196	.032	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NADK2-AS1–THCA

Open the THCA breakdown →