NADK

Across TCGA cell cohorts, NADK RNA expression is significantly associated with the go_rna of many other GO terms, with 4,937 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NADK-associated GO terms across cancer lineages are Regulation of transcription of nucleolar large rRNA by RNA polymerase I, Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I, and Response to methionine. Each is linked with NADK in more than 15 cancer types. Because this analysis shows association rather than direction, both NADK-to-partner and partner-to-NADK results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of transcription of nucleolar large rRNA by RNA polymerase I grouped by NADK-low versus NADK-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NADK→partner) and Y-score (partner→NADK) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BONE	Regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.144	+0.845	<.001	<.001	3	16
BONE	Positive regulation of transcription of nucleolar large rRNA by RNA polymerase I →	+0.144	+0.824	<.001	<.001	3	15
BONE	Response to methionine →	+0.111	+0.927	<.001	<.001	3	15
BONE	Cellular response to methionine →	+0.111	+0.927	<.001	<.001	3	15
BONE	Regulation of DNA repair →	+0.088	+1.001	.004	<.001	3	14
PANCREAS	Negative regulation of DNA-templated transcription initiation →	+0.152	+0.835	<.001	.001	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,937 associations by consensus.

Regulation of transcription of nucleolar large rRNA by RNA polymerase I by NADK expression — BONE

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