Across TCGA pan-cancer cohorts, NACAP7 RNA differs between tumor and matched normal tissue in 4 of 18 cancer types tested, making tumor–normal expression one of NACAP7’s most consistent transcriptional readouts.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where NACAP7 RNA is more highly expressed in tumor relative to normal tissue. In most cancer types NACAP7 is over-expressed in tumor, although a few such as BLCA show the opposite, repressed pattern.

KIRC, HNSC, and BLCA are the cancer types where NACAP7 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NACAP7 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
KIRC	All	All	+0.041	.001	6	view →
HNSC	Male	III,IV	+0.063	.027	4	view →
BLCA	Male	IV	−0.162	.027	1	view →
LIHC	Male	All	+0.029	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 4 strongest of 4 lineages.

Exploration

Same gene, other analysis: NACAP7 RNA expression & survival · all NACAP7 data types