Q-omics provides the consensus-scored NACAP7 profile across patient tissues and cancer cell-line models. NACAP7 expression is associated with patient survival in 10 of 34 cancer types, with the highest sampling consensus in THCA. Among the 18 cancer types available for tumor–normal comparison, NACAP7 is differentially expressed in 4, with the highest sampling consensus in KIRC. Additionally, NACAP7 RNA expression shows 6,233 significant pathway-activity associations, with the highest sampling consensus in STAD. Together, these results highlight THCA, KIRC, and STAD as cancer lineages where NACAP7 shows reproducible signals across survival, tumor–normal expression, and patient cross-omics analyses.
Every result is evaluated using two consensus scores. Sampling consensus measures how consistently a finding is reproduced within a cancer lineage across different conditions. Lineage consensus measures how broadly the result is shared across cancer types, distinguishing pan-cancer signals from lineage-specific patterns.
Premium analyses for NACAP7 — synthetic lethality, tumor antigen, and pembrolizumab response.
This table summarizes NACAP7 survival associations across molecular data types. NACAP7 RNA expression shows survival associations in the most cancer types (10). The rightmost column indicates the cancer type with the highest sampling consensus for each molecular layer.
This table ranks reproducible NACAP7 RNA expression–survival associations across cancer types. High NACAP7 expression shows unfavorable associations in KICH, ACC, LUSC and LIHC, but favorable associations in THCA and PRAD. The THCA Kaplan–Meier curve shows clear separation, with the low-expression group declining faster, consistent with the favorable association (log-rank p = .010). Together, the overview and detailed table identify THCA as the clearest survival context for NACAP7 RNA expression.
This table summarizes NACAP7 tumor–normal expression differences by data type. RNA shows broader differences across cancer types, with a lineage consensus of 4. The strongest signals are observed in KIRC for RNA.
This table ranks reproducible tumor–normal expression differences for NACAP7. A negative fold-change indicates higher expression in normal tissue than in tumor tissue. NACAP7 shows lower tumor expression in BLCA and higher tumor expression in KIRC, HNSC and LIHC. The KIRC box plot shows higher NACAP7 RNA expression in tumor versus normal tissue (log2 FC = +0.041, t-test p = .001).
This table shows molecular features associated with NACAP7 in patient tissues and cancer cell lines. In patient samples, NACAP7 shows the broadest associations at the RNA and protein expression levels, with STAD recurring as the lineage with the largest associated feature set.
